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Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease

Alzheimer’s disease (AD) poses an ever-increasing public health concern as the population ages, affecting more than 6 million Americans. AD patients present with mood and sleep changes in the prodromal stages that may be partly driven by loss of monoaminergic neurons in the brainstem, but a causal r...

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Detalles Bibliográficos
Autores principales: Khan, Kanza M., Balasubramanian, Nagalakshmi, Gaudencio, Gabriel, Wang, Ruixiang, Selvakumar, Govindhasamy Pushpavathi, Kolling, Louis, Pierson, Samantha, Tadinada, Satya M., Abel, Ted, Hefti, Marco, Marcinkiewcz, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069039/
https://www.ncbi.nlm.nih.gov/pubmed/37009893
http://dx.doi.org/10.1186/s40478-023-01546-5