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Connecting a disconnected trial network with a new trial: optimizing the estimation of a comparative effect in a network meta-analysis

BACKGROUND: In network meta-analysis, estimation of a comparative effect can be performed for treatments that are connected either directly or indirectly. However, disconnected trial networks may arise, which poses a challenge to comparing all available treatments of interest. Several modeling appro...

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Detalles Bibliográficos
Autores principales: McKeen, Lauren, Morris, Paul, Wang, Chong, Morris, Max D., O’Connor, Annette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069097/
https://www.ncbi.nlm.nih.gov/pubmed/37013490
http://dx.doi.org/10.1186/s12874-023-01896-7