Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma

BACKGROUND: We propose a new approach for designing personalized treatment for colorectal cancer (CRC) patients, by combining ex vivo organoid efficacy testing with mathematical modeling of the results. METHODS: The validated phenotypic approach called Therapeutically Guided Multidrug Optimization (...

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Detalles Bibliográficos
Autores principales: Ramzy, George M., Norkin, Maxim, Koessler, Thibaud, Voirol, Lionel, Tihy, Mathieu, Hany, Dina, McKee, Thomas, Ris, Frédéric, Buchs, Nicolas, Docquier, Mylène, Toso, Christian, Rubbia-Brandt, Laura, Bakalli, Gaetan, Guerrier, Stéphane, Huelsken, Joerg, Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069117/
https://www.ncbi.nlm.nih.gov/pubmed/37013646
http://dx.doi.org/10.1186/s13046-023-02650-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069117/
https://www.ncbi.nlm.nih.gov/pubmed/37013646
http://dx.doi.org/10.1186/s13046-023-02650-z

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