Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents

Immunomodulatory medications like thalidomide and its analogs prevent the production of some proinflammatory cytokines linked to cancer. A new series of thalidomide analogs were designed and synthesized in order to develop potential antitumor immunomodulatory agents. The antiproliferative activities...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotb, Anas Ramadan, Abdallah, Abdallah E., Elkady, Hazem, Eissa, Ibrahim H., Taghour, Mohammed S., Bakhotmah, Dina Abed, Abdelghany, Tamer M., El-Zahabi, Mohamed Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069230/
https://www.ncbi.nlm.nih.gov/pubmed/37021105
http://dx.doi.org/10.1039/d3ra00066d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069230/
https://www.ncbi.nlm.nih.gov/pubmed/37021105
http://dx.doi.org/10.1039/d3ra00066d

Ejemplares similares