The anti-sigma factor MucA is required for viability in Pseudomonas aeruginosa

During decades-long infections in the cystic fibrosis (CF) airway, Pseudomonas aeruginosa undergoes selection. One bacterial genetic adaptation often observed in CF isolates is mucA mutations. MucA inhibits the sigma factor AlgU. Mutations in mucA lead to AlgU misregulation, resulting in a mucoid ph...

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Detalles Bibliográficos
Autores principales: Schofield, Melissa C., Rodriguez, Daniela Q., Kidman, Amanda A., Cassin, Erin K., Michaels, Lia A., Campbell, Elizabeth A., Jorth, Peter A., Tseng, Boo Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069406/
https://www.ncbi.nlm.nih.gov/pubmed/33905139
http://dx.doi.org/10.1111/mmi.14732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069406/
https://www.ncbi.nlm.nih.gov/pubmed/33905139
http://dx.doi.org/10.1111/mmi.14732

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