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The evolving tale of Pol2 function

DNA replication is complex and highly regulated, and DNA replication errors can lead to human diseases such as cancer. DNA polymerase ε (polε) is a key player in DNA replication and contains a large subunit called POLE, which possesses both a DNA polymerase domain and a 3′–5′ exonuclease domain (EXO...

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Detalles Bibliográficos
Autores principales: Gallitto, Matthew, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069447/
https://www.ncbi.nlm.nih.gov/pubmed/36813532
http://dx.doi.org/10.1101/gad.350527.123