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The evolving tale of Pol2 function
DNA replication is complex and highly regulated, and DNA replication errors can lead to human diseases such as cancer. DNA polymerase ε (polε) is a key player in DNA replication and contains a large subunit called POLE, which possesses both a DNA polymerase domain and a 3′–5′ exonuclease domain (EXO...
Autores principales: | Gallitto, Matthew, Zhang, Zhiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069447/ https://www.ncbi.nlm.nih.gov/pubmed/36813532 http://dx.doi.org/10.1101/gad.350527.123 |
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