PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection

DNA double-strand break (DSB) repair is initiated by DNA end resection. CtIP acts in short-range resection to stimulate MRE11–RAD50–NBS1 (MRN) to endonucleolytically cleave 5′-terminated DNA to bypass protein blocks. CtIP also promotes the DNA2 helicase–nuclease to accelerate long-range resection do...

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Detalles Bibliográficos
Autores principales: Ceppi, Ilaria, Cannavo, Elda, Bret, Hélène, Camarillo, Rosa, Vivalda, Francesca, Thakur, Roshan Singh, Romero-Franco, Amador, Sartori, Alessandro A., Huertas, Pablo, Guérois, Raphaël, Cejka, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069449/
https://www.ncbi.nlm.nih.gov/pubmed/36746606
http://dx.doi.org/10.1101/gad.349981.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069449/
https://www.ncbi.nlm.nih.gov/pubmed/36746606
http://dx.doi.org/10.1101/gad.349981.122

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