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Complex hierarchical structures in single-cell genomics data unveiled by deep hyperbolic manifold learning

With the advances in single-cell sequencing techniques, numerous analytical methods have been developed for delineating cell development. However, most are based on Euclidean space, which would distort the complex hierarchical structure of cell differentiation. Recently, methods acting on hyperbolic...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Zhong, Cheng, Lin, Xiang, Wei, Zhi, Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069463/
https://www.ncbi.nlm.nih.gov/pubmed/36849204
http://dx.doi.org/10.1101/gr.277068.122