A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements

Pediatric pineoblastomas (PBs) are rare and aggressive tumors of grade IV histology. Although some oncogenic drivers are characterized, including germline mutations in RB1 and DICER1, the role of epigenetic deregulation and cis-regulatory regions in PB pathogenesis and progression is largely unknown...

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Detalles Bibliográficos
Autores principales: Idriss, Salam, Hallal, Mohammad, El-Kurdi, Abdullah, Zalzali, Hasan, El-Rassi, Inaam, Ehli, Erik A., Davis, Christel M., Chung, Philip E.D., Gendoo, Deena M.A., Zacksenhaus, Eldad, Saab, Raya, Khoueiry, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069464/
https://www.ncbi.nlm.nih.gov/pubmed/36650051
http://dx.doi.org/10.1101/gr.277037.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069464/
https://www.ncbi.nlm.nih.gov/pubmed/36650051
http://dx.doi.org/10.1101/gr.277037.122

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