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Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations

Background: Genetic interindividual variability is associated with adverse drug reactions (ADRs) and affects the response to common drugs used in anesthesia. Despite their importance, these variants remain largely underexplored in Latin-American countries. This study describes rare and common varian...

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Detalles Bibliográficos
Autores principales: Parada-Márquez, Juan Fernando, Maldonado-Rodriguez, Nicolás David, Triana-Fonseca, Paula, Contreras-Bravo, Nora Constanza, Calderón-Ospina, Carlos Alberto, Restrepo, Carlos M., Morel, Adrien, Ortega-Recalde, Oscar Javier, Silgado-Guzmán, Daniel Felipe, Angulo-Aguado, Mariana, Fonseca-Mendoza, Dora Janeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069477/
https://www.ncbi.nlm.nih.gov/pubmed/37021041
http://dx.doi.org/10.3389/fphar.2023.1047854