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A PET-CT study on neuroinflammation in Huntington’s disease patients participating in a randomized trial with laquinimod

Microglia activation, an indicator of central nervous system inflammation, is believed to contribute to the pathology of Huntington’s disease. Laquinimod is capable of regulating microglia. By targeting the translocator protein, (11)C-PBR28 PET-CT imaging can be used to assess the state of regional...

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Detalles Bibliográficos
Autores principales: Roussakis, Andreas-Antonios, Gennaro, Marta, Gordon, Mark Forrest, Reilmann, Ralf, Borowsky, Beth, Rynkowski, Gail, Lao-Kaim, Nicholas P, Papoutsou, Zoe, Savola, Juha-Matti, Hayden, Michael R, Owen, David R, Kalk, Nicola, Lingford-Hughes, Anne, Gunn, Roger N, Searle, Graham, Tabrizi, Sarah J, Piccini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069663/
https://www.ncbi.nlm.nih.gov/pubmed/37020532
http://dx.doi.org/10.1093/braincomms/fcad084