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A PET-CT study on neuroinflammation in Huntington’s disease patients participating in a randomized trial with laquinimod
Microglia activation, an indicator of central nervous system inflammation, is believed to contribute to the pathology of Huntington’s disease. Laquinimod is capable of regulating microglia. By targeting the translocator protein, (11)C-PBR28 PET-CT imaging can be used to assess the state of regional...
Autores principales: | Roussakis, Andreas-Antonios, Gennaro, Marta, Gordon, Mark Forrest, Reilmann, Ralf, Borowsky, Beth, Rynkowski, Gail, Lao-Kaim, Nicholas P, Papoutsou, Zoe, Savola, Juha-Matti, Hayden, Michael R, Owen, David R, Kalk, Nicola, Lingford-Hughes, Anne, Gunn, Roger N, Searle, Graham, Tabrizi, Sarah J, Piccini, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069663/ https://www.ncbi.nlm.nih.gov/pubmed/37020532 http://dx.doi.org/10.1093/braincomms/fcad084 |
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