Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

To prepare for future coronavirus (CoV) pandemics, it is desirable to generate vaccines capable of eliciting broadly neutralizing antibody responses to CoVs. Here, we show that immunization of macaques with SARS-CoV-2 spike (S) protein with a two-shot protocol generated potent serum receptor binding...

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Detalles Bibliográficos
Autores principales: He, Wan-ting, Yuan, Meng, Callaghan, Sean, Musharrafieh, Rami, Song, Ge, Silva, Murillo, Beutler, Nathan, Lee, Wen-Hsin, Yong, Peter, Torres, Jonathan L., Melo, Mariane, Zhou, Panpan, Zhao, Fangzhu, Zhu, Xueyong, Peng, Linghang, Huang, Deli, Anzanello, Fabio, Ricketts, James, Parren, Mara, Garcia, Elijah, Ferguson, Melissa, Rinaldi, William, Rawlings, Stephen A., Nemazee, David, Smith, Davey M., Briney, Bryan, Safonova, Yana, Rogers, Thomas F., Dan, Jennifer M., Zhang, Zeli, Weiskopf, Daniela, Sette, Alessandro, Crotty, Shane, Irvine, Darrell J., Ward, Andrew B., Wilson, Ian A., Burton, Dennis R., Andrabi, Raiees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069796/
https://www.ncbi.nlm.nih.gov/pubmed/35947674
http://dx.doi.org/10.1126/scitranslmed.abl9605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069796/
https://www.ncbi.nlm.nih.gov/pubmed/35947674
http://dx.doi.org/10.1126/scitranslmed.abl9605

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