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Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases

Secreted semaphorin 3F (Sema3F) and semaphorin 3A (Sema3A) exhibit remarkably distinct effects on deep layer excitatory cortical pyramidal neurons; Sema3F mediates dendritic spine pruning, whereas Sema3A promotes the elaboration of basal dendrites. Sema3F and Sema3A signal through distinct holorecep...

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Detalles Bibliográficos
Autores principales: Koropouli, Eleftheria, Wang, Qiang, Mejías, Rebeca, Hand, Randal, Wang, Tao, Ginty, David D, Kolodkin, Alex L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069869/
https://www.ncbi.nlm.nih.gov/pubmed/37010951
http://dx.doi.org/10.7554/eLife.83217