Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1

Polycystic kidney disease is a disorder of renal epithelial growth and differentiation. Transcription factor EB (TFEB), a master regulator of lysosome biogenesis and function, was studied for a potential role in this disorder. Nuclear translocation and functional responses to TFEB activation were st...

Descripción completa

Detalles Bibliográficos
Autores principales: Shillingford, Jonathan M., Shayman, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069964/
https://www.ncbi.nlm.nih.gov/pubmed/36794754
http://dx.doi.org/10.1152/ajprenal.00237.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069964/
https://www.ncbi.nlm.nih.gov/pubmed/36794754
http://dx.doi.org/10.1152/ajprenal.00237.2022

Ejemplares similares