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Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1
Polycystic kidney disease is a disorder of renal epithelial growth and differentiation. Transcription factor EB (TFEB), a master regulator of lysosome biogenesis and function, was studied for a potential role in this disorder. Nuclear translocation and functional responses to TFEB activation were st...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Physiological Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069964/ https://www.ncbi.nlm.nih.gov/pubmed/36794754 http://dx.doi.org/10.1152/ajprenal.00237.2022 |