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Apigenin improves cytotoxicity of antiretroviral drugs against HTLV-1 infected cells through the modulation of AhR signaling

OBJECTIVES: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory autoimmune disease characterized by high levels of infected immortalized T cells in circulation, which makes it difficult for antiretroviral (ART) drugs to work effectively. In previous studies, we...

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Detalles Bibliográficos
Autores principales: Sales, Dominic, Lin, Edward, Stoffel, Victoria, Dickson, Shallyn, Khan, Zafar K., Beld, Joris, Jain, Pooja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070013/
https://www.ncbi.nlm.nih.gov/pubmed/37027342
http://dx.doi.org/10.1515/nipt-2022-0017