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Dual-Peak Lorentzian CEST MRI for antiretroviral drug brain distribution

OBJECTIVES: Spatial–temporal biodistribution of antiretroviral drugs (ARVs) can now be achieved using MRI by utilizing chemical exchange saturation transfer (CEST) contrasts. However, the presence of biomolecules in tissue limits the specificity of current CEST methods. To overcome this limitation,...

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Detalles Bibliográficos
Autores principales: Liu, Yutong, Gauthier, Gabriel C., Gendelman, Howard E., Bade, Aditya N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070014/
https://www.ncbi.nlm.nih.gov/pubmed/37027345
http://dx.doi.org/10.1515/nipt-2022-0012