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Computational speed-up of large-scale, single-cell model simulations via a fully integrated SBML-based format

SUMMARY: Large-scale and whole-cell modeling has multiple challenges, including scalable model building and module communication bottlenecks (e.g. between metabolism, gene expression, signaling, etc.). We previously developed an open-source, scalable format for a large-scale mechanistic model of pro...

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Detalles Bibliográficos
Autores principales: Mutsuddy, Arnab, Erdem, Cemal, Huggins, Jonah R, Salim, Misha, Cook, Daniel, Hobbs, Nicole, Feltus, F Alex, Birtwistle, Marc R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070034/
https://www.ncbi.nlm.nih.gov/pubmed/37020976
http://dx.doi.org/10.1093/bioadv/vbad039