Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis

OBJECTIVES: To present an unbiased approach to identify positional transcript single nucleotide polymorphisms (SNPs) of osteoarthritis (OA) risk loci by allelic expression imbalance (AEI) analyses using RNA sequencing of articular cartilage and subchondral bone from OA patients. METHODS: RNA sequenc...

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Detalles Bibliográficos
Autores principales: Coutinho de Almeida, Rodrigo, Tuerlings, Margo, Ramos, Yolande, Den Hollander, Wouter, Suchiman, Eka, Lakenberg, Nico, Nelissen, Rob G H H, Mei, Hailiang, Meulenbelt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070069/
https://www.ncbi.nlm.nih.gov/pubmed/36040165
http://dx.doi.org/10.1093/rheumatology/keac498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070069/
https://www.ncbi.nlm.nih.gov/pubmed/36040165
http://dx.doi.org/10.1093/rheumatology/keac498

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