Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice

The pronounced choleretic properties of 24-norUrsodeoxycholic acid (norUDCA) to induce bicarbonate-rich bile secretion have been attributed to its ability to undergo cholehepatic shunting. The goal of this study was to identify the mechanisms underlying the choleretic actions of norUDCA and the role...

Descripción completa

Detalles Bibliográficos
Autores principales: Truong, Jennifer K., Li, Jianing, Li, Qin, Pachura, Kimberly, Rao, Anuradha, Gumber, Sanjeev, Fuchs, Claudia Daniela, Feranchak, Andrew P., Karpen, Saul J., Trauner, Michael, Dawson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070106/
https://www.ncbi.nlm.nih.gov/pubmed/36787187
http://dx.doi.org/10.1172/jci.insight.149360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070106/
https://www.ncbi.nlm.nih.gov/pubmed/36787187
http://dx.doi.org/10.1172/jci.insight.149360

Ejemplares similares