Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation

As a hallmark of inflammatory bowel disease (IBD), elevated intestinal epithelial cell (IEC) death compromises the gut barrier, activating the inflammatory response and triggering more IEC death. However, the precise intracellular machinery that prevents IEC death and breaks this vicious feedback cy...

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Detalles Bibliográficos
Autores principales: Xu, Jiaqi, Li, Shihao, Jin, Wei, Zhou, Hui, Zhong, Tingting, Cheng, Xiaoqing, Fu, Yujuan, Xiao, Peng, Cheng, Hongqiang, Wang, Di, Ke, Yuehai, Jiang, Zhinong, Zhang, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070107/
https://www.ncbi.nlm.nih.gov/pubmed/36795486
http://dx.doi.org/10.1172/jci.insight.162701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070107/
https://www.ncbi.nlm.nih.gov/pubmed/36795486
http://dx.doi.org/10.1172/jci.insight.162701

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