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EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids

Epithelial organoids derived from intestinal tissue, called enteroids, recapitulate many aspects of the organ in vitro and can be used for biological discovery, personalized medicine, and drug development. Here, we interrogated the cell signaling environment within the developing human intestine to...

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Detalles Bibliográficos
Autores principales: Childs, Charlie J., Holloway, Emily M., Sweet, Caden W., Tsai, Yu-Hwai, Wu, Angeline, Vallie, Abigail, Eiken, Madeline K., Capeling, Meghan M., Zwick, Rachel K., Palikuqi, Brisa, Trentesaux, Coralie, Wu, Joshua H., Pellón-Cardenas, Oscar, Zhang, Charles J., Glass, Ian, Loebel, Claudia, Yu, Qianhui, Camp, J. Gray, Sexton, Jonathan Z., Klein, Ophir D., Verzi, Michael P., Spence, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070114/
https://www.ncbi.nlm.nih.gov/pubmed/36821371
http://dx.doi.org/10.1172/jci.insight.165566