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EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids
Epithelial organoids derived from intestinal tissue, called enteroids, recapitulate many aspects of the organ in vitro and can be used for biological discovery, personalized medicine, and drug development. Here, we interrogated the cell signaling environment within the developing human intestine to...
Autores principales: | Childs, Charlie J., Holloway, Emily M., Sweet, Caden W., Tsai, Yu-Hwai, Wu, Angeline, Vallie, Abigail, Eiken, Madeline K., Capeling, Meghan M., Zwick, Rachel K., Palikuqi, Brisa, Trentesaux, Coralie, Wu, Joshua H., Pellón-Cardenas, Oscar, Zhang, Charles J., Glass, Ian, Loebel, Claudia, Yu, Qianhui, Camp, J. Gray, Sexton, Jonathan Z., Klein, Ophir D., Verzi, Michael P., Spence, Jason R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070114/ https://www.ncbi.nlm.nih.gov/pubmed/36821371 http://dx.doi.org/10.1172/jci.insight.165566 |
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