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Cancer-associated mesothelial cell–derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis

Ovarian cancer (OvCa) preferentially metastasizes in association with mesothelial cell–lined surfaces. We sought to determine if mesothelial cells are required for OvCa metastasis and detect alterations in mesothelial cell gene expression and cytokine secretion upon interaction with OvCa cells. Usin...

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Detalles Bibliográficos
Autores principales: Bajwa, Preety, Kordylewicz, Kasjusz, Bilecz, Agnes, Lastra, Ricardo R., Wroblewski, Kristen, Rinkevich, Yuval, Lengyel, Ernst, Kenny, Hilary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070116/
https://www.ncbi.nlm.nih.gov/pubmed/36795484
http://dx.doi.org/10.1172/jci.insight.163019