Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer

Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibition of E-cadherin (CDH1) expression. Recently, EM plasticity (EMP) and E-cadherin–mediated, cluster-based metastasis and treatment resistance have become more...

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Detalles Bibliográficos
Autores principales: Balamurugan, Kuppusamy, Poria, Dipak K., Sehareen, Saadiya W., Krishnamurthy, Savitri, Tang, Wei, McKennett, Lois, Padmanaban, Veena, Czarra, Kelli, Ewald, Andrew J., Ueno, Naoto T., Ambs, Stefan, Sharan, Shikha, Sterneck, Esta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070121/
https://www.ncbi.nlm.nih.gov/pubmed/36757813
http://dx.doi.org/10.1172/jci.insight.156057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070121/
https://www.ncbi.nlm.nih.gov/pubmed/36757813
http://dx.doi.org/10.1172/jci.insight.156057

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