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The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis
The oxidative balance of a cell is maintained by the Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway. This cytoprotective pathway detoxifies reactive oxygen species and xenobiotics. The role of the KEAP1/NRF2 pathway as pro-tumorigenic or anti-t...
Autores principales: | Occhiuto, Christopher J., Moerland, Jessica A., Leal, Ana S., Gallo, Kathleen A., Liby, Karen T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070161/ https://www.ncbi.nlm.nih.gov/pubmed/36994476 http://dx.doi.org/10.14348/molcells.2023.2191 |
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