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Molecular Basis of the KEAP1-NRF2 Signaling Pathway

Transcription factor NRF2 (NF-E2-related factor 2) is a master regulator of cellular responses against environmental stresses. NRF2 induces expression of detoxification and antioxidant enzymes and suppresses inductions of pro-inflammatory cytokine genes. KEAP1 (Kelch-like ECH-associated protein 1) i...

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Detalles Bibliográficos
Autores principales: Suzuki, Takafumi, Takahashi, Jun, Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070164/
https://www.ncbi.nlm.nih.gov/pubmed/36994473
http://dx.doi.org/10.14348/molcells.2023.0028