Intratumoral Heterogeneity and Clonal Evolution Induced by HPV Integration

The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive cancers, but the consequences for chromosomal integrity are unknown. Continuous long-read sequencing of oropharyngeal cancers and cancer cell lines identified a previously undescribed form of structural variation,...

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Detalles Bibliográficos
Autores principales: Akagi, Keiko, Symer, David E., Mahmoud, Medhat, Jiang, Bo, Goodwin, Sara, Wangsa, Darawalee, Li, Zhengke, Xiao, Weihong, Dunn, Joe Dan, Ried, Thomas, Coombes, Kevin R., Sedlazeck, Fritz J., Gillison, Maura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070172/
https://www.ncbi.nlm.nih.gov/pubmed/36715691
http://dx.doi.org/10.1158/2159-8290.CD-22-0900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070172/
https://www.ncbi.nlm.nih.gov/pubmed/36715691
http://dx.doi.org/10.1158/2159-8290.CD-22-0900

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