Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis

Ribosomally synthesized and post-translationally modified peptide natural products have provided many highly unusual scaffolds. This includes the intriguing alkaloids crocagins, which possess a tetracyclic core structure and whose biosynthesis has remained enigmatic. Here we use in vitro experiments...

Descripción completa

Detalles Bibliográficos
Autores principales: Adam, Sebastian, Zheng, Dazhong, Klein, Andreas, Volz, Carsten, Mullen, William, Shirran, Sally L., Smith, Brian O., Kalinina, Olga V., Müller, Rolf, Koehnke, Jesko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070186/
https://www.ncbi.nlm.nih.gov/pubmed/36894702
http://dx.doi.org/10.1038/s41557-023-01153-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070186/
https://www.ncbi.nlm.nih.gov/pubmed/36894702
http://dx.doi.org/10.1038/s41557-023-01153-w

Ejemplares similares