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Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling

FGF/FGFR signaling is critical for the development and homeostasis of the human body and imbalanced FGF/FGFR contributes to the progression of severe diseases, including cancers. FGFRs are N-glycosylated, but the role of these modifications is largely unknown. Galectins are extracellular carbohydrat...

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Detalles Bibliográficos
Autores principales: Zukowska, Dominika, Gedaj, Aleksandra, Porebska, Natalia, Pozniak, Marta, Krzyscik, Mateusz, Czyrek, Aleksandra, Krowarsch, Daniel, Zakrzewska, Malgorzata, Otlewski, Jacek, Opalinski, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070233/
https://www.ncbi.nlm.nih.gov/pubmed/37012400
http://dx.doi.org/10.1007/s00018-023-04768-x