Cargando…
PEACOCK: a machine learning approach to assess the validity of cell type-specific enhancer-gene regulatory relationships
The vast majority of disease-associated variants identified in genome-wide association studies map to enhancers, powerful regulatory elements which orchestrate the recruitment of transcriptional complexes to their target genes’ promoters to upregulate transcription in a cell type- and timing-depende...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070356/ https://www.ncbi.nlm.nih.gov/pubmed/37012250 http://dx.doi.org/10.1038/s41540-023-00270-z |