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Immortal-time bias in older vs younger age groups: a simulation study with application to a population-based cohort of patients with colon cancer

BACKGROUND: In observational studies, the risk of immortal-time bias (ITB) increases with the likelihood of early death, itself increasing with age. We investigated how age impacts the magnitude of ITB when estimating the effect of surgery on 1-year overall survival (OS) in patients with Stage IV co...

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Detalles Bibliográficos
Autores principales: Pilleron, Sophie, Maringe, Camille, Morris, Eva J. A., Leyrat, Clémence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070415/
https://www.ncbi.nlm.nih.gov/pubmed/36759725
http://dx.doi.org/10.1038/s41416-023-02187-0