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Immortal-time bias in older vs younger age groups: a simulation study with application to a population-based cohort of patients with colon cancer
BACKGROUND: In observational studies, the risk of immortal-time bias (ITB) increases with the likelihood of early death, itself increasing with age. We investigated how age impacts the magnitude of ITB when estimating the effect of surgery on 1-year overall survival (OS) in patients with Stage IV co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070415/ https://www.ncbi.nlm.nih.gov/pubmed/36759725 http://dx.doi.org/10.1038/s41416-023-02187-0 |