MNT suppresses T cell apoptosis via BIM and is critical for T lymphomagenesis

The importance of c-MYC in regulating lymphopoiesis and promoting lymphomagenesis is well-established. Far less appreciated is the vital supporting role of MYC’s relative MNT. Using Rag1Cre-mediated Mnt deletion in lymphoid progenitor cells, we show here that, during normal T cell development, MNT l...

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Detalles Bibliográficos
Autores principales: Nguyen, Hai Vu, Vandenberg, Cassandra J., Robati, Mikara R., Ng, Ashley P., Cory, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070419/
https://www.ncbi.nlm.nih.gov/pubmed/36755068
http://dx.doi.org/10.1038/s41418-023-01119-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070419/
https://www.ncbi.nlm.nih.gov/pubmed/36755068
http://dx.doi.org/10.1038/s41418-023-01119-y

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