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NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive type of lung cancer driven by combined loss of the tumor suppressors RB1 and TP53. SCLC is highly metastatic and despite good initial response to chemotherapy patients usually relapse, resulting in poor survival. Therefore, better understanding of the m...

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Detalles Bibliográficos
Autores principales: Koerner, Lioba, Schmiel, Marcel, Yang, Tsun-Po, Peifer, Martin, Buettner, Reinhard, Pasparakis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070460/
https://www.ncbi.nlm.nih.gov/pubmed/36653597
http://dx.doi.org/10.1038/s41418-023-01112-5