Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma

Myeloid cells comprise the majority of immune cells in tumors, contributing to tumor growth and therapeutic resistance. Incomplete understanding of myeloid cells response to tumor driver mutation and therapeutic intervention impedes effective therapeutic design. Here, by leveraging CRISPR/Cas9-based...

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Detalles Bibliográficos
Autores principales: Chen, Zhihong, Soni, Nishant, Pinero, Gonzalo, Giotti, Bruno, Eddins, Devon J., Lindblad, Katherine E., Ross, James L., Puigdelloses Vallcorba, Montserrat, Joshi, Tanvi, Angione, Angelo, Thomason, Wes, Keane, Aislinn, Tsankova, Nadejda M., Gutmann, David H., Lira, Sergio A., Lujambio, Amaia, Ghosn, Eliver E. B., Tsankov, Alexander M., Hambardzumyan, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070461/
https://www.ncbi.nlm.nih.gov/pubmed/37012245
http://dx.doi.org/10.1038/s41467-023-37361-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070461/
https://www.ncbi.nlm.nih.gov/pubmed/37012245
http://dx.doi.org/10.1038/s41467-023-37361-8

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