Cargando…

The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells

The DNA damage response (DDR) plays crucial roles in cancer prevention and therapy. Poly(ADP-ribose) polymerase 1 (PARP1) mediates multiple signal transduction in the DDR as a master regulator. Uncovering the regulatory factors of PARP1 contributes to a more comprehensive view of tumorigenesis and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Haoxiu, Liu, Chao, Han, Fang, Lin, Xiaoyu, Cao, Liangyu, Liu, Chenxing, Ji, Qiuyu, Cui, Jinjin, Yao, Yuanfei, Wang, Bojun, liao, Yuanyu, Nie, Huan, Zhang, Yanqiao, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070477/
https://www.ncbi.nlm.nih.gov/pubmed/36750717
http://dx.doi.org/10.1038/s41418-023-01118-z