Cargando…

The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells

The DNA damage response (DDR) plays crucial roles in cancer prevention and therapy. Poly(ADP-ribose) polymerase 1 (PARP1) mediates multiple signal transduction in the DDR as a master regulator. Uncovering the regulatory factors of PARP1 contributes to a more comprehensive view of tumorigenesis and t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Haoxiu, Liu, Chao, Han, Fang, Lin, Xiaoyu, Cao, Liangyu, Liu, Chenxing, Ji, Qiuyu, Cui, Jinjin, Yao, Yuanfei, Wang, Bojun, liao, Yuanyu, Nie, Huan, Zhang, Yanqiao, Li, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070477/ https://www.ncbi.nlm.nih.gov/pubmed/36750717 http://dx.doi.org/10.1038/s41418-023-01118-z

Ejemplares similares

Epigenetic modifications inhibit the expression of MARVELD1 and in turn tumorigenesis by regulating the Wnt/β-catenin pathway in pan-cancer
por: Zhang, Jingchun, et al.
Publicado: (2022)

Biological and clinical significance of epigenetic silencing of MARVELD1 gene in lung cancer
por: Shi, Ming, et al.
Publicado: (2014)

ACVRL1 drives resistance to multitarget tyrosine kinase inhibitors in colorectal cancer by promoting USP15-mediated GPX2 stabilization
por: Lu, Xiaolin, et al.
Publicado: (2023)

A CTCF-Binding Element and Histone Deacetylation Cooperatively Maintain Chromatin Loops, Linking to Long-Range Gene Regulation in Cancer Genomes
por: Tang, Ran, et al.
Publicado: (2022)

MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development
por: Liu, Weizhe, et al.
Publicado: (2018)

Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer
por: Liu, Chao, et al.
Publicado: (2021)

MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1
por: Hu, Jianran, et al.
Publicado: (2013)

C1orf109L binding DHX9 promotes DNA damage depended on the R‐loop accumulation and enhances camptothecin chemosensitivity
por: Dou, Peng, et al.
Publicado: (2020)

MarvelD3 couples tight junctions to the MEKK1–JNK pathway to regulate cell behavior and survival
por: Steed, Emily, et al.
Publicado: (2014)

Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling
por: Vacca, Barbara, et al.
Publicado: (2018)

A Rare Mutation in the MARVELD2 Gene Can Cause Nonsyndromic Hearing Loss
por: Sadeghi, Zahra, et al.
Publicado: (2020)

PARP Power: A Structural Perspective on PARP1, PARP2, and PARP3 in DNA Damage Repair and Nucleosome Remodelling
por: van Beek, Lotte, et al.
Publicado: (2021)

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
por: Steed, Emily, et al.
Publicado: (2009)

High expression of MARVELD3 as a potential prognostic biomarker for oral squamous cell carcinoma
por: Huang, Ke, et al.
Publicado: (2022)

PARP1 associates with R-loops to promote their resolution and genome stability
por: Laspata, Natalie, et al.
Publicado: (2023)

G-Quadruplex loops regulate PARP-1 enzymatic activation
por: Edwards, Andrea D, et al.
Publicado: (2020)

PARP-1 inhibitors enhance the chemosensitivity of leukemia cells by attenuating NF- кB pathway activity and DNA damage response induced by Idarubicin : PARP-1 inhibitors attenuate DNA damage response
por: Ke, Bo, et al.
Publicado: (2021)

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response
por: Kim, Chiho, et al.
Publicado: (2020)

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo
por: Shao, Zhengping, et al.
Publicado: (2020)

Ubiquitin specific peptidase 5 enhances STAT3 signaling and promotes migration and invasion in Pancreatic Cancer
por: Lian, Jie, et al.
Publicado: (2020)

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions
por: Raleigh, David R., et al.
Publicado: (2010)

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus
por: Vacca, Barbara, et al.
Publicado: (2016)

Spatio-temporal expression pattern and role of the tight junction protein MarvelD3 in pancreas development and function
por: Heymans, Charlotte, et al.
Publicado: (2021)

SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism
por: Luna, Augustin, et al.
Publicado: (2013)

Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization
por: Bell, Nicholas A. W., et al.
Publicado: (2021)

Up-regulation of MARVEL domain-containing protein 1 (MARVELD1) accelerated the malignant phenotype of glioma cancer cells via mediating JAK/STAT signaling pathway
por: Xia, Lingyang, et al.
Publicado: (2021)

PARP-1: Friend or Foe of DNA Damage and Repair in Tumorigenesis?
por: Swindall, Amanda F., et al.
Publicado: (2013)

Role of tight junction-associated MARVEL protein marvelD3 in migration and epithelial–mesenchymal transition of hepatocellular carcinoma
por: Li, Yanmeng, et al.
Publicado: (2021)

MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier
por: Weiß, Franziska, et al.
Publicado: (2022)

DNA damage induced by KP372-1 hyperactivates PARP1 and enhances lethality of pancreatic cancer cells with PARP inhibition
por: Viera, Talysa, et al.
Publicado: (2020)

Nuclear DJ-1 Regulates DNA Damage Repair via the Regulation of PARP1 Activity
por: Wang, Zhong-Xuan, et al.
Publicado: (2023)

Uncoupling of PARP1 Trapping and Inhibition Using Selective PARP1 Degradation
por: Wang, Shuai, et al.
Publicado: (2019)

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites
por: Lin, Xiaohui, et al.
Publicado: (2022)

STAT1-mediated inhibition of FOXM1 enhances gemcitabine sensitivity in pancreatic cancer
por: Liu, Chao, et al.
Publicado: (2019)

MARVELD2 (DFNB49) Mutations in the Hearing Impaired Central European Roma Population - Prevalence, Clinical Impact and the Common Origin
por: Mašindová, Ivica, et al.
Publicado: (2015)

PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage
por: Martire, Sara, et al.
Publicado: (2013)

Characterization of the interactions of PARP-1 with UV-damaged DNA in vivo and in vitro
por: Purohit, Nupur K., et al.
Publicado: (2016)

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition
por: Aguilar-Quesada, Rocío, et al.
Publicado: (2007)

Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging
por: Mahadevan, Jyothi, et al.
Publicado: (2022)

PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs
por: Wang, Luyao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_d5afk2804g2j2ns3sgb3o4q9u9