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Hydrogen/deuterium exchange-mass spectrometry of integral membrane proteins in native-like environments: current scenario and the way forward

Integral membrane proteins (IMPs) perform a range of diverse functions and their dysfunction underlies numerous pathological conditions. Consequently, IMPs constitute most drug targets, and the elucidation of their mechanism of action has become an intense field of research. Historically, IMP studie...

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Detalles Bibliográficos
Autores principales: Javed, Waqas, Griffiths, Damon, Politis, Argyris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070480/
https://www.ncbi.nlm.nih.gov/pubmed/36876893
http://dx.doi.org/10.1042/EBC20220173