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Distinct transcriptomic and epigenomic modalities underpin human memory T cell subsets and their activation potential
Human memory T cells (MTC) are poised to rapidly respond to antigen re-exposure. Here, we derived the transcriptional and epigenetic programs of resting and ex vivo activated, circulating CD4(+) and CD8(+) MTC subsets. A progressive gradient of gene expression from naïve to T(CM) to T(EM) is observe...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070634/ https://www.ncbi.nlm.nih.gov/pubmed/37012418 http://dx.doi.org/10.1038/s42003-023-04747-9 |