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Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent

The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spaceflight, associated with, for example, musculoskeletal atroph...

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Detalles Bibliográficos
Autores principales: Malhan, Deeksha, Yalçin, Müge, Schoenrock, Britt, Blottner, Dieter, Relógio, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070655/
https://www.ncbi.nlm.nih.gov/pubmed/37012297
http://dx.doi.org/10.1038/s41526-023-00273-4