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Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent
The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spaceflight, associated with, for example, musculoskeletal atroph...
Autores principales: | Malhan, Deeksha, Yalçin, Müge, Schoenrock, Britt, Blottner, Dieter, Relógio, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070655/ https://www.ncbi.nlm.nih.gov/pubmed/37012297 http://dx.doi.org/10.1038/s41526-023-00273-4 |
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