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The three-dimensionality of the hiPSC-CM spheroid contributes to the variability of the field potential

Background: Field potential (FP) signals from human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) spheroid which are used for drug safety tests in the preclinical stage are different from action potential (AP) signals and require working knowledge of the multi-electrode array (MEA)...

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Detalles Bibliográficos
Autores principales: Hwang, Minki, Lee, Su-Jin, Lim, Chul-Hyun, Shim, Eun Bo, Lee, Hyang-Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070703/
https://www.ncbi.nlm.nih.gov/pubmed/37025386
http://dx.doi.org/10.3389/fphys.2023.1123190