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Pathophysiology of Ca(v)1.3 L-type calcium channels in the heart

Ca(2+) plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca(2+) regulation alters the force of contraction and causes cardiac arrhythmias. Ca(2+) entry into cardiomyocytes is mediated mainly through L-type Ca(2+) channels, leading to the subsequent Ca(2+) rel...

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Detalles Bibliográficos
Autores principales: Zaveri, Sahil, Srivastava, Ujala, Qu, Yongxia Sarah, Chahine, Mohamed, Boutjdir, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070707/
https://www.ncbi.nlm.nih.gov/pubmed/37025382
http://dx.doi.org/10.3389/fphys.2023.1144069