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Dynamic changes of enhancer and super enhancer landscape in degenerated nucleus pulposus cells

Inflammatory cascade and extracellular matrix remodeling have been identified as pivotal pathological factors in the progression of intervertebral disc degeneration (IDD), but the mechanisms underlying the aberrant activation of transcription during nucleus pulposus (NP) cell degeneration remain elu...

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Detalles Bibliográficos
Autores principales: Li, Guowang, Kang, Yuxiang, Feng, Xiangling, Wang, Guohua, Yuan, Yue, Li, Zhenhua, Du, Lilong, Xu, Baoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070812/
https://www.ncbi.nlm.nih.gov/pubmed/37012048
http://dx.doi.org/10.26508/lsa.202201854