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SOCS3 as a potential driver of lung metastasis in colon cancer patients

BACKGROUND: The suppressor of cytokine signaling 3 (SOCS3) is the negative feedback regulator of the JAK-STAT signaling pathway. The purpose of our study was to investigate the SOCS3 status in colon primary tumor and lung metastasis and its relationship with macrophages. METHODS: The SOCS3 expressio...

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Detalles Bibliográficos
Autores principales: Li, Xuejie, Yang, Zuyi, Chen, Bi, Gu, Lei, Tian, Guoyan, Sui, Xinbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10070831/
https://www.ncbi.nlm.nih.gov/pubmed/37025997
http://dx.doi.org/10.3389/fimmu.2023.1088542