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Patients with hypercortisolemic Cushing disease possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis

Although human cell cultures stimulated with dexamethasone suggest that the glucocorticoid receptor (GR) activates stress erythropoiesis, the effects of GR activation on erythropoiesis in vivo remain poorly understood. We characterized the phenotype of a large cohort of patients with Cushing disease...

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Detalles Bibliográficos
Autores principales: Varricchio, Lilian, Geer, Eliza B., Martelli, Fabrizio, Mazzarini, Maria, Funnell, Alister, Bieker, James J., Papayannopoulou, Thalia, Migliaccio, Anna Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071118/
https://www.ncbi.nlm.nih.gov/pubmed/35861015
http://dx.doi.org/10.3324/haematol.2021.280542