Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia

Persistence of residual disease in acute lymphoblastic leukemia (ALL) during the initial stages of chemotherapy is associated with inferior survival. To better understand clonal evolution and mechanisms of chemoresistance, we used multiparameter mass cytometry, at single-cell resolution, to function...

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Detalles Bibliográficos
Autores principales: Masic, Dino, Fee, Kayleigh, Bell, Hayden L., Case, Marian, Witherington, Gabby, Lansbury, Sophie, Ojeda-Garcia, Juan, McDonald, David, Schwab, Claire, van Delft, Frederik W., Filby, Andrew, Irving, Julie Anne Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Acute Lymphoblastic Leukemia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071119/
https://www.ncbi.nlm.nih.gov/pubmed/36420798
http://dx.doi.org/10.3324/haematol.2022.281177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071119/
https://www.ncbi.nlm.nih.gov/pubmed/36420798
http://dx.doi.org/10.3324/haematol.2022.281177

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