Development of UPLC method for simultaneous assay of some COVID-19 drugs utilizing novel instrumental standard addition and factorial design

A green, rapid, and simple RP-UPLC method was developed and optimized by full factorial design for the simultaneous separation of oseltamivir phosphate, daclatasivir dihydrochloride, and remdesivir, with dexamethasone as a co-administered drug. The separation was established on a UPLC column BEH C(1...

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Detalles Bibliográficos
Autores principales: El-Shorbagy, Hanan I., Mohamed, Mona A., El-Gindy, Alaa, Hadad, Ghada M., Belal, Fathalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071232/
https://www.ncbi.nlm.nih.gov/pubmed/37016018
http://dx.doi.org/10.1038/s41598-023-32405-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071232/
https://www.ncbi.nlm.nih.gov/pubmed/37016018
http://dx.doi.org/10.1038/s41598-023-32405-x

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